Changing in timings administration of the supplement can effect the success of the treatment.
A dose on empty stomach early in the morning is generally more effective. The rule is that when the patient is strong and the disease serious, supplements should be taken on an empty stomach in the morning.
There are two other methods:
The first method is best for Snehpana and Rasayana, The second is best for Kwaths (Kashaya) and other treatments.
These methods are superior to all other methods. If the patient is weak, they may not stand the strain of Pathya and the potency of the supplement.
A further method is to take the supplement on an empty stomach before the evening meal, allowing at least one hour before and take a far smaller dose. After the dose and after the meal, one should lie on the left side for a while.
(Chikitsa Samgraham, Vaidyaratanam S Varier 2004)